Publications for WUSTL, TAMU, UCB, UCSB, UTSW

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  1. Zhang F, Smolen JA, Zhang S, Li R, Shah PN, Cho S, Wang H, Raymond JE, Cannon CL, Wooley KL. "Degradable Polyphosphoester-Based Silver-Loaded Nanoparticles as Therapeutics for Bacterial Lung Infections." Nanoscale, 2015 Jan 28, 7(6):2265-70. Available online at DOI: 10.1039/c4nr07103d. PMID: 25573163.

  2. Zhegalova NG, Dergunov SA, Wang ST, Pinkhassik E, Berezin MY. "Design of Fluorescent Nanocapsules as Ratiometric Nanothermometers." Chemistry, 2014 Aug 11, 20(33):10292-7. Available online at DOI: 10.1002/chem.201402828. Epub 2014 Jul 13. PMID: 25044240.

  3. He X, Fan J, Zhang F, Li R, Pollack KA, Raymond JE, Zou J, Wooley KL. "Multi-Responsive Hydrogels Derived from the Self-Assembly of Tethered Allyl-Functionalized Racemic Oligopeptides." J Mater Chem B, 2014. Available online at DOI: 10.1039/C4TB00909F. Epub 2014 Jul 23.

  4. Lim YH, Heo GS, Rezenom YH, Pollack S, Raymond JE, Elsabahy M, Wooley KL. "Development of a Vinyl Ether-Functionalized Polyphosphoester as a Template for Multiple Postpolymerization Conjugation Chemistries and Study of Core Degradable Polymeric Nanoparticles." Macromolecules, 2014 Jul 22, 47(14):4634-44. Available online at DOI: 10.1021/ma402480a. Epub 2014 Jul 2.

  5. Zou J, He X, Fan J, Raymond JE, Wooley KL. "Supramolecularly Knitted Tethered Oligopeptide/Single-Walled Carbon Nanotube Organogels." Chemistry, 2014 Jul 14, 20(29):8842-7. Available online at DOI: 10.1002/chem.201403027. Epub 2014 Jun 24. PMID: 24961389. PMCID: PMC4139973.

  6. Fan J, Li R, He X, Seetho K, Zhang F, Zou J, Wooley KL. "Construction of a Versatile and Functional Nanoparticle Platform Derived from a Helical Diblock Copolypeptide-Based Biomimetic Polymer." Polym Chem, 2014 Jul 7, 5(13):3977-81. PMID: 25013459. PMCID: PMC4084918.

  7. Klinger D, Wang CX, Connal LA, Audus DJ, Jang SG, Kraemer S, Killops KL, Fredrickson GH, Kramer EJ, Hawker CJ. "A Facile Synthesis of Dynamic, Shape-Changing Polymer Particles." Angew Chem Int Ed Engl, 2014 Jul 1, 53(27):7018-22. Available online at DOI: 10.1002/anie.201400183. Epub 2014 Apr 2. PMID: 24700705. PMCID: PMC4074252.

  8. Noel A, Borquet YP, Raymond JE, Wooley KL. "Poly(carbonate-amide)s Derived from Bio-Based Resources: Poly(ferulic acid-co-tyrosine)." Macromolecules, 2014 May 13, 47(9):2974-83. Epub 2014 Apr 16. PMID: 24839309. PMCID: PMC4020594.

  9. Zhegalova NG, He S, Zhou H, Kim DM, Berezin MY. "Minimization of Self-Quenching Fluorescence on Dyes Conjugated to Biomolecules with Multiple Labeling Sites via Asymetrically Charged NIR Fluorophores." Contrast Media Mol Imaging, 2014 Sep, 9(5):355-62. Available online at DOI: 10.1002/cmmi.1585. Epub 2014 Apr 25. PMID: 24764130. PMCID: PMC4198576.

  10. Heo GS, Cho S, Wooley KL. "Aldehyde-Functional Polycarbonates as Reactive Platforms." Polym Chem, 2014 Jun 7, 5:3555-8. Available online at DOI: 10.1039/C4PY00456F. Epub 2014 Apr 23.

  11. Leuhmann HP, Pressly ED, Detering L, Wang C, Pierce R, Woodard PK, Gropler RJ, Hawker CJ, Liu Y. "PET/CT Imaging of Chemokine Receptor CCR5 in Vascular Injury Model Using Targeted Nanoparticle." J Nucl Med, 2014 Apr 1, 55(4):629-34. Available online at DOI: 10.2967/jnumed.113.132001. Epub 2014 Mar 3. PMID: 24591489. PMCID: PMC4255944.

  12. Krupnick AS, Lin X, Li W, Higashikubo R, Zinselmeyer BH, Hartzler H, Toth K, Ritter JH, Berezin MY, Wang ST, Miller MJ, Gelman AE, Kreisel D. "Central Memory CD8+ T Lymphocytes Mediate Lung Allograft Acceptance." J Clin Invest, 2014 Mar 3, 124(3):1130-43. Available online at DOI: 10.1172/JCI71359. Epub 2014 Feb 24. PMID: 24569377. PMCID: PMC3938255.

  13. Zou J, Zhang F, Zhang S, Pollack SF, Elsabahy M, Fan J, Wooley KL. "Poly(ethylene oxide)-block-polyphosphoester-graft-paclitaxel Conjugates with Acid-Labile Linkages as a pH-Sensitive and Functional Nanoscopic Platform for Paclitaxel Delivery." Adv Healthc Mater, 2014 Mar, 3(3):441-8. Available online at DOI: 10.1002/adhm.201300235. Epub 2013 Aug 30. PMID: 23997013. PMCID: PMC3938983.

  14. Samarajeewa S, Zentay RP, Jhurry ND, Li A, Seetho K, Zou J, Wooley KL. "Programmed Hydrolysis of Nanoassemblies by Electrostatic Interaction-Mediated Enzymatic-Degradation." Chem Commun (Camb), 2014 Jan 28, 50(8):968-70. Available online at DOI: 10.1039/c3cc46013d. PMID: 24301076. PMCID: PMC4165354.

  15. Gustafson TP, Lim YH, Flores JA, Heo GS, Zhang F, Zhang S, Samarajeewa S, Raymond JE, Wooley KL. "Holistic Assessment of Covalently Labelled Core-Shell Polymeric Nanoparticles with Fluorescent Contrast Agents Towards Theranostic Applications." Langmuir, 2014 Jan 21, 30(2):631-41. Available online at DOI: 10.1021/la403943w. Epub 2014 Jan 6. PMID: 24392760. PMCID: PMC3933954.

  16. Zhao Y, Sultan D, Detering L, Cho S, Sun G, Pierce R, Wooley KL, Liu Y. "Copper-64-Alloyed Gold Nanoparticles for Cancer Imaging: Improved Radiolabel Stability and Diagnostic Accuracy." Agnew Chem Int Ed Engl, 2014 Jan 3, 53(1):156-9. Available online at DOI: 10.1002/anie.201308494. Epub 2013 Nov 24. PMID: 24272951.

  17. Fan J, Zou J, He X, Zhang F, Zhang S, Raymond JE, Wooley KL. "Tunable Mechano-Responsive Organogels by Ring-Opening Copolymerizations of N-carboxyanhydrides." Chem Sci, 2014 Jan, 5(2). Available online at DOI:10.1039/C3SC52504J. PMID: 24363890. PMCID: PMC3865608.

  18. Elsabahy M, Li A, Zhang F, Sultan D, Liu Y, Wooley KL. "Differential Immunotoxicities of Poly(ethylene glycol)- vs. Poly(carboxybetaine)-Coated Nanoparticles." J Control Release, 2013 Dec 28, 172(3):641-52. Available online at DOI: 10.1016/j.jconrel.2013.09.010. Epub 2013 Sep 20. PMID: 24056145. PMCID: PMC3858532.

  19. Lee A, Lundberg P, Klinger D, Lee BF, Hawker CJ, Lynd NA. "Physiologically Relevant, pH-Responsive PEG-Based Block and Statistical Copolymers with N,N-Diisopropylamine Units." Polym Chem, 2013 Dec 21, 4(24):5735-42. Available online at DOI: 10.1039/C3PY00747B. Epub 2013 Jul 16.

  20. Zhegalova NG, Gonzales G, Berezin MY. "Synthesis of Nitric Oxide Probes with Fluorescence Lifetime Sensitivity." Org Biomol Chem, 2013 Dec 21, 11(47):8228-34. Available online at DOI: 10.1039/c3ob41498a. Epub 2013 Oct 28. PMID: 24166035. PMCID: PMC3872128.

  21. Elsabahy M, Zhang S, Zhang F, Deng ZJ, Lim YH, Wang H, Parsamian P, Hammond PT, Wooley KL. "Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles." Sci Rep, 2013 Nov 22, 3:3313. Available online at DOI: 10.1038/srep03313. PMID: 24264796. PMCID: PMC3837308.

  22. Elsabahy M, Samarajeewa S, Raymond JE, Clark C, Wooley KL. "Shell-Crosslinked Knedel-Like Nanoparticles Induce Lower Immunotoxicity Than Their Non-Crosslinked Analogs." J Mater Chem B, 2013 Oct 21, 1(39):5241-5255. Available online at DOI: 10.1039/c3tb20668h. Epub 2013 Jun 18. PMID: 24187610. PMCID: PMC3811931.

  23. Shen Y, Zhang S, Zhang F, Loftis A, Pavia-Sanders A, Zou J, Fan J, Taylor JS, Wooley KL. "Polyphosphoester-Based Cationic Nanoparticles Serendipitously Release Integral Biologically-Active Components to Serve as Novel Degradable Inducible Nitric Oxide Synthase Inhibitors." Adv Mater, 2013 Oct 18, 25(39):5609-14. Available online at DOI: 10.1002/adma.201302842. Epub 2013 Sep 3. PMID: 23999874.

  24. Klinger D, Robb MJ, Spruell JM, Lynd NA, Hawker CJ, Connal LA. "Supramolecular Guests in Solvent Driven Block Copolymer Assembly: From Internally Structured Nanoparticles to Micelles." Polym Chem, 2013 Oct 7, 4(19):5038-42. Available online at DOI: 10.1039/C3PY00750B. Epub 2013 Jul 5.

  25. Zhang Z, Liu Y, Jarreau C, Welch MJ, Taylor JS. "Nucleic Acid-Directed Self-Assembly of Multifunctional Gold Nanoparticle Imaging Agents." Biomater Sci, 2013 Oct 1, 1(10):1055-64. Available online at DOI: 10.1039/c3bm60070j. Epub 2013 Jun 20. PMID: 24058728. PMCID: PMC3777812.

  26. Cao Q, Zhegalova NG, Wang ST, Akers WJ, Berezin MY. "Multispectral Imaging in the Extended NIR Window Based on Endogenous Chromophores." J Biomed Opt, 2013 Oct, 18(10):101318. Available online at DOI: 10.1117/1.JBO.18.10.101318. PMID: 23933967. PMCID: PMC3739874.

  27. Iorger TR, O'Malley T, Liao R, Guinn KM, Hickey MJ, Mohaideen N, Murphy KC, Boshoff HI, Mizrahi V, Rubin EJ, Sassetti CM, Barry CE 3rd, Sherman DR, Parish T, Sacchettini JC. "Identification of New Drug Targets in Mycobacterium Tuberculosis". PLoS One, 2013 Sep 23, 8(9):e75245. Available online at DOI: 10.1371/journal.pone.0075245. PMID: 24086479. PMCID: PMC3781026.

  28. Gustafson TP, Lonnecker AT, Heo GS, Zhang S, Dove AP, Wooley KL. "Poly(D-Glucose Carbonate) Block Copolymers: A Platform for Natural Product-Based Nanomaterials with Solvothermatic Characteristics." Biomacromolecules, 2013 Sep 9, 14(9):3346-53. Available online at DOI: 10.1021/bm4010832. Epub 2013 Aug 19. PMID: 23957247.

  29. Lim YH, Heo GS, Cho S, Wooley KL. "Construction of a Reactive Diblock Copolymer, Polyphosphoester-block-Poly(L-lactide), as a Versatile Framework for Functional Materials that are Capable of Full Degradation and Nanoscopic Assembly Formation." ACS Macro Lett, 2013 Aug 19, 2(9). Available online at DOI: 10.1021/mz400229m. PMID: 24167757. PMCID: PMC3808001.

  30. Magalotti S, Gustafson TP, Cao Q, Abendschein DR, Pierce R, Berezin MY, Akers WJ. "Evaluation of Inflammatory Response to Acute Ischemia Using Near-Infrared Fluorescent Reactive Oxygen Sensors." Mol Imaging Biol, 2013 Aug, 15(4):423-30. Available online at DOI: 10.1007/s11307-013-0614-2. PMID: 23378226. PMCID: PMC3940059.

  31. Wang ST, Zhegalova NG, Gustafson TP, Zhou A, Sher J, Achilefu S, Berezin OY, Berezin MY. "Sensitivity of Activatable ROS Probes by Fluorescence Spectroelectrochemistry." Analyst, 2013 Aug 7, 138(15):4363-9. Available online at DOI: 10.1039/c3an00459g. Epub 2013 Jun 4. PMID: 23736882. PMCID: PMC3722072.

  32. Zou J, Zhang F, Chen Y, Raymond J, Zhang S, Fan J, Zhu J, Li A, Seetho K, He X, Pochan DJ, Wooley KL. "Responsive Organogels Formed by Supramolecular Self Assembly of PEG-Block-Allyl-Functionalized Polypeptides into β-Sheet-Driven Polymeric Ribbons." Soft Matter, 2013 Jul 10, 9:5951-8. Available online at DOI: 10.1039/c3sm50582k. Epub 2013 May 21.

  33. Zhang S, Wang H, Shen Y, Zhang F, Seetho K, Zou J, Taylor JS, Dove AP, Wooley KL. "A Simple and Efficient Synthesis of an Acid-Labile Polyphosphoramidate by Organobase-Catalyzed Ring-Opening Polymerization and Transformation to Polyphosphoester Ionomers by Acid Treatment." Macromolecules, 2013 Jul 9, 46(13):5141-9. PMID: 23997276. PMCID: PMC3755629.

  34. Liu Y, Pierce R, Luehmann HP, Sharp TL, Welch MJ. "PET Imaging of Chemokine Receptors in Vascular Injury Accelerated Atherosclerosis." J Nucl Med, 2013 Jul 1, 54(7):1135-41. Available online at DOI: 10.2967/jnumed.112.114777. Epub 2013 May 8. PMID: 23658218. PMCID: PMC4251467.

  35. Shah PN, Lin LY, Smolen JA, Tagaev JA, Gunsten SP, Hans DS, Heo GS, Li Y, Zhang F, Zheng S, Wright BD, Panzner MJ, Youngs WJ, Brody SL, Wooley KL, Cannon CL. "Synthesis, Characterization, and In Vivo Efficacy of Shell Cross-Linked Nanoparticle Formulations Carrying Silver Antimicrobials as Aerosolized Therapeutics." ACS Nano, 2013 Jun 25, 7(6):4977-87. Available online at DOI: 10.1021/nn400322f. Epub 2013 Jun 4. PMID: 23718195. PMCID: PMC4287418.

  36. Elsabahy M, Wooley KL. "Cytokines as Biomarkers of Nanoparticle Immunotoxicity." Chem Soc Rev, 2013 Jun 21, 42(12):5552-76. Available online at DOI: 10.1039/c3cs60064e. PMID: 23549679. PMCID: PMC3665642.

  37. Aweda TA, Ikotun O, Mastren T, Cannon CL, Wright B, Youngs WJ, Cutler C, Guthrie J, Lapi SE. "The Use of 111Ag as a Tool for Studying Biological Distribution of Silver-Based Antimicrobials." Medchemcomm, 2013 Jun 1, 4(6):1015-7. PMID: 23930200. PMCID: PMC3733397.

  38. Zou J, Fan J, He X, Zhang S, Wang H, Wooley KL. "A Facile Glovebox-Free Strategy to Significantly Accelerate the Syntheses of Well-Defined Polypeptides by N-Carboxyanhydride (NCA) Ring Opening Polymerizations." Macromolecules, 2013 May 28, 46(10):4223-6. PMID: 23794753. PMCID: PMC3686519.

  39. Elsabahy M, Shrestha R, Clark C, Taylor S, Leonard J, Wooley KL. "Multifunctional Hierarchically-Assembled Nanostructures as Complex Stage-Wise Dual-Delivery Systems for Coincidental yet Differential Trafficking of siRNA and Paclitaxel." Nano Lett, 2013 May 8, 13(5):2172-81. Available online at DOI: nl4006645. Epub 2013 Apr 10. PMID: 23574430. PMCID: PMC3681414.

  40. Zhang S, Zou J, Elsabahy M, Karwa A, Li A, Moore DA, Dorshow RB, Wooley KL. "Poly(ethylene oxide)-Block-Polyphosphester-Based Paclitaxel Conjugates as a Platform for Ultra-High Paclitaxel-Loaded Multifunctional Nanoparticles." Chem Sci, 2013 May 1, 4(5):2122-6. Available online at DOI: 10.1039/c3sc50252j. Epub 2013 Mar 6. PMID: 25152808. PMCID: PMC4138828.

  41. Guo Y, Aweda T, Black K, Liu Y. "Development of Radiolabeled Nanoparticles for Theranostic Applications." Special Issue on Imaging Agents in Medicinal Chemistry and Drug Discovery in Current Topics in Medicinal Chemistry. In Press.

  42. Shen Y, Shrestha R, Ibricevic A, Gunsten SP, Welch MJ, Wooley KL, Brody SL, Taylor JS, Liu Y. "Antisense Peptide Nucleic Acid-Functionalized Cationic Nanocomplex for In Vivo mRNA Detection." Interface Focus, 2013 Apr 23, 2012:0059. Available online at DOI: 10.1098/rsfs.2012.0059. Epub 2013 Mar 3. PMID: 24427537. PMCID: PMC3638413.

  43. Shen Y, Fang H, Zhang K, Shrestha R, Wooley KL, Taylor JS. “Efficient Protection and Transfection of siRNA by Cationic Shell-Crosslinked Knedel-like Nanoparticles (cSCKs)”. Nucleic Acid Ther, 2013 Apr, 23(2):95-108. Available online at DOI: 10.1089/nat.2012.0390. PMID: 23557117. PMCID: PMC3619153.

  44. Samarajeewa S, Ibricevic A, Gunsten SP, Shrestha R, Elsabahy M, Brody SL, Wooley KL. "Degradable Cationic Shell Cross-Linked Knedel-Like Nanoparticles: Synthesis, Degradation, Nucleic Acid Binding, and In Vitro Evaluation." Biomacromolecules, 2013 Apr 8, 14(4):1018-27. Available online at DOI: 10.1021/bm3018774. Epub 2013 Mar 19. PMID: 23510389. PMCID: PMC3640429.

  45. Wang Z, Zhang K, Shen Y, Smith J, Bloch S, Achilefu S, Wooley KL, Taylor JS. “Imaging mRNA Expression Levels in Living Cells with PNA∙DNA Binary FRET Probes Delivered by Cationic Shell-Crosslinked Nanoparticles.” Org Biomol Chem, 2013 May 21, 11(19):3159-67. Available online at DOI: 10.1039/c3ob26923j. Epub 2013 Mar 28. PMID: 23538604. PMCID: PMC3687806.

  46. Ibircevic A, Gunsten SP, Zhang K, Shrestha R, Liu Y, Sun JY, Welch MJ, Wooley KL, Brody SL. "PEGylation of Cationic, Shell-Crosslinked-Knedel-Like Nanoparticles Modulates Inflammation and Enhances Cellular Uptake in the Lung." Nanomedicine, 2013 Oct; 9(7):912-22. Available online at DOI: 10.1016/j.nano.2013.02.006. Epub 2013 Feb 27. PMID: 23453959. PMCID: PMC3724762.

  47. Pressly ED, Pierce RA, Connal LA, Hawker CJ, Liu Y. "Nanoparticle PET/CT Imaging of Natriuretic Peptide Clearance Receptor in Prostate Cancer." Bioconjug Chem, 2013 Feb 20, 24(2):196-204. Available online at DOI: 10.1021/bc300473x. Epub 2013 Jan 11. PMID: 23272904. PMCID: PMC3578065.

  48. Gustafson TP, Dergunov SA, Akers WJ, Chen Q, Magalotti S, Achilefu S, Pinkhassik E, Berezin MY. "Blood Triggered Rapid Release Porous Nanocapsules." RCS Adv, 2013 Jan 24, 3(16):5547-5555. Available online at DOI: 10.1039/C3RA22693J. PMID: 23606942. PMCID: PMC3627417.

  49. Albertazzi L, Mickler FM, Pavan GM, Salomone F, Bardi G, Panniello M, Amir E, Kang T, Killops KL, Bräuchle C, Amir RJ, Hawker CJ. "Enhanced Bioactivity of Internally Functionalized Cationic Dendrimers with PEG Cores." Biomacromolecules, 2012 Dec 10, 13(12):4089–4097. Available online at DOI: 10.1021/bm301384y. Epub 2012 Nov 27. PMID: 21340570. PMCID: PMC3524974.

  50. Lundberg P, Lee BF, van den Berg SA, Pressly ED, Lee A, Hawker CJ, Lynd NA. "Poly[(ethylene oxide)-co-(methylene ethylene oxide)]: A Hydrolytically Degradable Poly(ethylene oxide) Platform." ACS Macro Lett, 2012 Nov 20, 1(11):1240–1243. Epub 2012 Oct 10. PMID 23205320. PMCID: PMC3509790.

  51. Connal LA, Lynd NA, Robb MJ, See KA, Jang SG, Spruell JM, Hawker CJ. "Mesostructured Block Copolymer Nanoparticles: Versatile Templates for Hybrid Inorganic/Organic Nanostructures." Chem Mater, 2012 Nov 13, 24(21):4036–4042. Epub 2012 Oct 15. PMID: 23335837. PMCID: PMC3546830.

  52. Zhang S, Zou J, Zhang F, Elsabahy M, Felder SE, Zhu J, Wooley KL. "Rapid and Versatile Construction of Diverse and Functional Nanostructures Derived from a Polyphosphoester-Based Biomimetic Block Copolymer System." J Am Chem Soc, 2012 Nov 7, 134(44):18467-74. Available online at DOI: 10.1021/ja309037m. Epub 2012 Oct 23. PMID: 23092249. PMCID: PMC3500909.

  53. Ornelas-Megiatto C, Shah PN, Wich PR, Cohen J, Tagaev JA, Smolen JA, Wright BD, Youngs WJ, Fréchet JMJ, Cannon CL. "Aerosolized Antimicrobial Agents Based on Degradable Dextran Nanoparticles Loaded with Silver Carbene Complexes." Mol Pharm, 2012 Nov 5, 9(11):3012-3022. Available online at DOI: 10.1021/mp3004379. Epub 2012 Oct 19. PMID 23025592. PMCID: PMC3579655.

  54. Shrestha R, Elsabahy M, Luehmann H, Samarajeewa S, Florez-Malaver S, Lee NS, Welch MJ, Liu Y, Wooley KL. "Hierarchically Assembled Theranostic Nanostructures for siRNA Delivery and Imaging Applications." J Am Chem Soc, 2012 Oct 24, 134(42)17362-5. Available online at DOI: 10.1021/ja306616n. Epub 2012 Oct 10. PMID: 23050597. PMCID: PMC3485678.

  55. Li A, Luehmann HP, Sun G, Samarajeewa S, Zou J, Zhang S, Zhang F, Welch MJ, Liu Y, Wooley KL. "Synthesis and In Vivo Pharmacokinetic Evaluation of Degradable Shell Crosslinked Polymer Nanoparticles with Poly(carboxybetaine) vs. Poly(ethylene glycol) Surface-grafted Coatings". ACS Nano, 2012 Oct 23, 6(10):8970-8982. Available online at DOI: 10.1021/nn303030t. Epub 2012 Oct 8. PMID 23043240. PMCID: PMC3485677. NIHMSID: 41368.

  56. Lundberg P, Lynd NA, Zhang Y, Zeng X, Krogstad DV, Paffen T, Malkoch M, Nyström AM, Hawker CJ. "pH-Triggered Self-Assembly of Biocompatible Histamine-Functionalized Triblock Copolymers." Soft Matter, 2013, 9:82–89. Available online at DOI: 10.1039/c2sm26996a. Epub 2012 Oct 15.

  57. Wang Z, Zhang K, Wooley KL, Taylor JS. “Imaging mRNA Expression in Live Cells via PNA·DNA Strand Displacement-Activated Probes.” J Nucleic Acids, 2012, 2012:962652. Available online at DOI: 10.1155/2012/962652. Epub 2012 Sep 26. PMID: 23056921. PMCID: PMC3463960.

  58. Shrestha R, Elsabahy M, Florez-Malaver S, Samarajeewa S, Wooley KL. "Endosomal Escape and Efficient siRNA Delivery by Optimization of Cationic Shell Crosslinked Knedel-like Nanoparticles with Tunable Buffering Capacities". Biomaterials, 2012 Nov, 33(33):8557-8568. Available online at DOI: 10.1016/j.biomaterials.2012.07.054. Epub 2012 Aug 16. PMID: 22901966. PMCID: PMC3582407. NIHMSID: 398995.

  59. Cauët SI, Lee NS, Lin LY, Wooley KL. "Individual Nano-Objects Obtained via Hierarchical Assembly of Polymer Building Blocks." In: Matyjaszewski K and Möller M (eds.) Polymer Science: A Comprehensive Reference, Vol 6, pp. 775–820. 2012 Amsterdam: Elsevier BV.

  60. Zeng D, Lee NS, Liu Y, Zhou D, Dence C, Wooley KL, Katzenellenbogen JA, Welch MJ. “64Cu Core-Labeled Nanoparticles with High Specific Activity via Metal-Free Click Chemistry.” ACS Nano, 2012 Jun 26, 6(6):5209-19. Available online at DOI: 10.1021/nn300974s. Epub 2012 May 8. PMID: 22548282. PMCID: PMC3383893.

  61. Amir E, Antoni P, Campos LM, Damiron D, Gupta N, Amir RJ, Pesika N, Drockenmuller E, Hawker CJ. "Biodegradable, Multi-Layered Coatings for Controlled Release of Small Molecules." Chem Commun, 2012 May 18; 48(40):4833-5. Available online at DOI: 10.1039/c2cc31188g. Epub 2012 Apr 12. PMID: 22499161.

  62. Elsabahy M, Wooley KL. “Strategies Toward Well-Defined Polymer Nanoparticles Inspired by Nature: Chemistry Versus Versatility.” J Polym Sci Part A: Polym Chem, 2012 May 15, 50(10):1869-1880. Available online at DOI: 10.1002/pola.25955. Epub 2012 Feb 20.

  63. Lee BF, Wolffs M, Delaney KT, Sprafke JK, Leibfarth FA, Hawker CJ, Lynd NA. “Reactivity Ratios and Mechanistic Insight for Anionic Ring-Opening Copolymerization of Epoxides.” Macromolecules, 2012 May 8, 45(9):3722-3731. Epub 2012 Apr 17. PMID: 23226879. PMCID: PMC3514019.

  64. Ibricevic A, Gunsten SP, Shrestha R, Sun JY, Taylor J-SA, Wooley KL, Brody SL. “Cationic Charged Polymer-Based Nanoparticles as Vehicles for In Vivo siRNA Delivery to Alveolar Macrophages in a Lung Inflammation Model.” Am J Respir Crit Care Med, 2012, 185:A2140.

  65. Liu Y, Welch MJ. "Nanoparticles Labeled with Positron Emitting Nuclides: Advantages, Methods, and Applications." Bioconjug Chem, 2012 Apr 18, 23(4):671-82. Available online at DOI: 10.1021/bc200264c. Epub 2012 Feb 6. PMID: 22242601. PMCID: PMC3329595.

  66. Robb MJ, Connal LA, Lee BF, Lynd NA, Hawker CJ. "Functional Block Copolymer Nanoparticles: Toward the Next Generation of Delivery Vehicles." Polym Chem, Epub 2012 Apr 18, 3:1618-1628. Available online at DOI: 10.1039/c2py20131c.

  67. Elsabahy M, Wooley K. "Design of Polymeric Nanoparticles for Biomedical Delivery Applications." Chem Soc Rev, 2012 Apr 7, 41(7):2545-61. Available online at DOI: 10.1039/c2cs15327k. Epub 2012 Feb 14. PMID: 22334259. PMCID: PMC3299918.

  68. Zhang X, Bloch S, Akers W, Achilefu S. “Near-Infrared Molecular Probes for In Vivo Imaging.” Curr Protoc Cytom, 2012 Apr, 12:12.27. Available online at DOI: 10.1002/0471142956.cy1227s60. PMID: 22470154. PMCID: PMC3334312.

  69. Shrestha R, Shen Y, Pollack KA, Taylor JS, Wooley KL. “Dual Peptide Nucleic Acid- and Peptide-Functionalized Shell Cross-Linked Nanoparticles Designed to Target mRNA Toward the Diagnosis and Treatment of Acute Lung Injury”. Bioconjug Chem, 2012 Mar 21, 23(3):574-85. Available online at DOI: 10.1021/bc200629f. Epub 2012 Feb 28. PMID: 22372643. PMCID: PMC3321742.

  70. Tang R, Lee H, Achilefu S. “Induction of pH Sensitivity on the Fluorescence Lifetime of Quantum Dots by NIR Fluorescent Dyes.” J Am Chem Soc, 2012 Mar 14; 134(10):4545-8. Available online at DOI: 10.1021/ja300276s. Epub 2012 Feb 28. PMID: 22360301. PMCID: PMC3303939.

  71. Gustafson TP, Yan Y, Newton P, Hunter DA, Achilefu S, Akers WJ, Mackinnon SE, Johnson PJ, Berezin MY. "A NIR Dye for Development of Peripheral Nerve Targeted Probes." MedChemComm, 2012 Mar 1, 3:685-690. Available online at DOI: 10.1039/C2MD00297C. Epub 2012 Jan 30. PMID: 24575295. PMCID: PMC3932509.

  72. Zhang S, Li A, Zou J, Lin LY, Wooley KL. "Facile Synthesis of Clickable, Water-Soluble, and Degradable Polyphosphoesters." ACS Macro Lett, 2012 Feb 21, 1(2):328–333. Available online at DOI: 10.1021/mz200226m. Epub 2012 Feb 3. PMID: 22866244. PMCID: PMC3410554.

  73. Gustafson TP, Cao Q, Achilefu S, Berezin MY. "Defining a Polymethine Dye for Fluorescence Anisotropy Applications in the Near-Infrared Spectral Range." Chemphyschem, 2012 Feb, 13(3):716-23. Available online at DOI: 10.1002/CPHC.201100916. Epub 2012 Feb 2. PMID: 22302715. PMCID: PMC3969755.

  74. Ornelas-Megiatto C, Wich PR, Fréchet JMJ. "Polyphosphonium Polymers for siRNA Delivery: An Efficient and Non-Toxic Alternative to Polyammonium Carriers." J Am Chem Soc, 2012 Feb 1, 134(4):1902-5. Available online at DOI: 10.1021/ja207366k. Epub 2012 Jan 19. PMID: 22239619.

  75. Guo K, Achilefu S, Berezin MY. "Dating Bloodstains with Fluorescence Lifetime Measurements." Chemistry, Eur J, 2012 Jan 27. Available online at DOI: 10.1002/chem.201102935. Epub 2012 Jan 4. PMID: 22238188. PMCID: PMC3494294. Featured in Chemistry World and Education in Chemistry magazines.

  76. Samarajeewa S, Shrestha R, Li Y, Wooley K. "Degradability of Poly(Lactic Acid)-Containing Nanoparticles: Enzymatic Access Through a Cross-Linked Shell Barrier." J Am Chem Soc, 2012 Jan 18, 134(2):1235-42. Available online at DOI: 10.1021/ja2095602. Epub 2011 Dec 13. PMID: 22257265. PMCID: PMC3265020.

  77. Zou J, Zhang S, Shrestha R, Seetho K, Donley CL, Wooley KL. “pH-Triggered Reversible Morphological Inversion of Orthogonally-Addressable Poly(3-acrylamidophenylboronic acid)-block-poly(acrylamidoethylamine) Micelles and their Shell Crosslinked Nanoparticles.” J Polym Sci Part A: Polym Chem, 2012 Jan 1, 3(11):3146-3156. Available online at DOI: 10.1039/C2PY20324C. Epub 2012 Jun 28. NIHMSID: 391196. PMID: 23185105. PMCID: PMC3505036.

  78. Liu Y, Pressly ED, Abendschein DR, Hawker CJ, Woodard GE, Woodard PK, Welch MJ. "Targeting Angiogenesis Using a C-Type Atrial Natriuretic Factor-Conjugated Nanoprobe and PET." J Nucl Med, 2011 Dec 1, 52(12):1956-63. Available online at DOI: 10.2967/jnumed.111.089581. Epub 2011 Nov 2. PMID: 22049461. PMCID: PMC4255943.

  79. Wich PR, Fréchet JMJ. “Degradable Dextran Particles for Gene Delivery Applications.” Austral J Chem, 2011 Nov 29, 65(1):15-19. Available online at DOI: 10.1071/ch11370.

  80. Nyström AM, Wooley KL. “The Importance of Chemistry in Creating Well-Defined Nanoscopic Embedded Therapeutics: Devices Capable of the Dual Functions of Imaging and Therapy.” Acc Chem Res, 2011 Oct 18, 44(10):969-978. Available online at DOI: 10.1021/ar200097k. Epub 2011 Jun 15. NIHMSID: 304595. PMID: 21675721. PMCID: PMC3196832.

  81. Lo Conte M, Robb MJ, Hed Y, Marra A, Malkoch M, Hawker CJ, Dondoni A. “Exhaustive Glycosylation, PEGylation, and Glutathionylation of a [G4]-ene(48) Dendrimer via Photoinduced Thiol-ene Coupling.” J Polym Sci Part A: Polym Chem, 2011 Oct 15, 49(20):4468-4475. PMID: 21966092. PMCID: PMC3181107.

  82. Lee BF, Kade MJ, Chute JA, Gupta N, Campos LM, Fredrickson GH, Kramer EJ, Lynd NA, Hawker CJ. “Poly(allyl Glycidyl Ether) - A Versatile and Functional Polyether Platform.” J Polym Sci Part A: Polym Chem, 2011 Oct 15, 49(20):4498-4504. PMID: 21966093. PMCID: PMC3181110.

  83. Lin BF, Marullo RS, Robb MJ, Krogstad DV, Antoni P, Hawker CJ, Campos LM, Tirrell MV. “De Novo Design of Bioactive Protein-Resembling Nanospheres via Dendrimer-Templated Peptide Amphiphile Assembly.” Nano Lett, 2011 Sep 14, 11(9):3946-50. Available online at DOI: 10.1021/nl202220q. Epub 2011 Aug 3. PMID: 21800917. PMCID: PMC3223106.

  84. Zhang S, Li Z, Samarajeewa S, Sun G, Yang C, Wooley KL. “Orthogonally Dual-Clickable Janus Nanoparticles Templated Against Functional Nanoscopic Substrates.” J Am Chem Soc, 2011 Jul 27, 133(29):11046-11049. Available online at DOI: 100.1021/ja203133h. Epub 2011 Jul 6. NIHMSID: 309962. PMID: 21732605. PMCID: PMC3148585.

  85. Lee NS, Sun G, Lin LY, Neumann WL, Freskos JN, Karwa A, Shieh JJ, Dorshow RB, Wooley KL. “Tunable Dual-Emitting Shell-Crosslinked Nano-Objects as Single-Component Ratiometric pH-Sensing Materials.” J Mater Chem, Epub 2011 Jun 27, 21(37):14193-14202. Available online at DOI: 10.1039/C1JM11854D.

  86. Sun G, Cui H, Yun Lin L, Lee NS, Yang C, Neumann WL, Freskos JN, Shieh JJ, Dorshow RB, Wooley KL. "Multicompartment Polymer Nanostructures with Ratiometric Dual-Emission pH-Sensitivity." J Am Chem Soc, 2011 Jun 8, 133(22):8534-43. Available online at DOI: 10.1021/ja200182t. Epub 2011 May 16. PMID: 21574617. PMCID: PMC3108251.

  87. Amir RJ, Albertazzi L, Willis J, Khan A, Kang T, Hawker CJ. "Multi-Functional Trackable Dendritic Scaffolds and Delivery Agents." Angew Chem, 2011 Apr 4, 50(15):3425-9. Available online at DOI: 10.1002/anie.201007427. Epub 2011 Mar 9. PMID: 21391296. PMCID: PMC3491073.

  88. Shokeen M, Pressly ED, Hagooly A, Zheleznyak A, Ramos N, Fiamengo AL, Welch MJ, Hawker CJ, Anderson CJ. “Evaluation of Multivalent, Functional Polymeric Nanoparticles for Imaging Applications.” ACS Nano, 2011 Feb 22, 5(2):738-47. Available online at DOI: 10.1021/nn102278w. Epub 2011 Jan 28. PMID: 21275414. PMCID: PMC3043165.

  89. Pressly ED, Amir RJ, Hawker CJ. “Rapid Synthesis of Block and Cyclic Copolymers via Click Chemistry in the Presence of Copper Nanoparticles.” J Polym Sci Part A: Polym Chem, 2011 Feb, 49(3):814-819. PMID: 21532941. PMCID: PMC3083830.


  1. Harring, S.D., "Natriuretic Peptide Receptor-C is Upregulated in Diseased Carotid Neointima", 2011 National Predoctoral Clinical Research Training Program Meeting, St. Louis, MO, May 12, 2011.

  2. Wooley, K.L., “Tailoring of nanoscopic devices through chemistry”, American Association for Cancer Research Symposium: Nano in Cancer: Linking chemistry, biology, and clinical applications in vivo, Miami, FL, January 13, 2011.

  3. Wooley, K.L., “Sophisticated Plastics: Diverse opportunities – from materials to medicine – for well-defined polymer chemistry”, Hope College, Department of Chemistry, Holland, MI, December 3, 2010.

  4. Wooley, K.L., “Sophisticated Plastics: Diverse opportunities – from materials to medicine – for well-defined polymer chemistry”, Trinity University, Department of Chemistry, San Antonio, TX, November 11, 2010.

  5. Wooley, K.L., “Complex macromolecular and nanoscale structures by combinations of living radical and ring opening polymerizations”, 2010 Aldrich Symposium in Materials Science, University of Michigan, Ann Arbor, MI, November 8, 2010.


  1. Berezin MY, Gustafson T. "Nanothermometer, Method and Uses Therefor." Filed by Washington University, 2013 Nov 27. Published 2014 May 29. US Patent Application No. 14/091,948.

  2. Lee BF, Lundberg P, van den Berg S, Pressly EP, Hawker CJ, Lynd NA. "Hydrolytically Degradable Poly-(Ethylene Glycol) Derivatives Through Introduction of Unsaturated Methylene-(Ethylene Oxide) Repeat Units." Filed by Washington University, 2013 Mar 15. Published 2013 Oct 17. U.S. Patent Application No. 2013/031,882.

  3. Woodard P, Rossin R, Woodard G, Welch M. "Natriuretic Peptide-Mediated Imaging of Atherosclerotic Plaque." Filed by Washington University, 2009 May 22. Published 2013 May 7. U.S. Patent No. 8,436,140.

  4. Guo K, Achilefu S, Berezin MY. "Dating Bloodstains and Biological Fluids with Fluorescence Lifetime Techniques." Filed by Washington University, 2012 Nov 30. Published 2013 May 30. US Patent Application No. 2013/0137127 A1.

  5. Woodard P, Liu Y, Pressly E, Hawker C, Abenschein DR. "Targeting NPR-C in Angiogenesis and Atherosclerosis with a C-Type Atrial Natriuretic Factor (CANF)-COMB Nanocomplex." Filed by Washington University, 2011 Jun 3. Published 2011 Dec 8. U.S. Patent Application No. 2011/030,071.

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